OPSUMIT® is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT® can:
Women who are able to get pregnant must have negative pregnancy tests:
Blood vessels in your lungs may be affected when there is either too much or too little of certain naturally occurring substances in your body: endothelin, nitric oxide, and/or prostacyclin. There are PAH treatments available that target each of these pathways:
Endothelin receptor antagonists (ERAs), such as OPSUMIT®, target this pathway.
Learn about the benefits of OPSUMIT®.
Phosphodiesterase type 5 inhibitors (PDE5 inhibitors) and soluble guanylate cyclase stimulators (sGCs) target this pathway.
Prostacyclin, prostacyclin analogs, and prostacyclin receptor agonists target this pathway.
Endothelin receptor antagonists (ERAs), such as OPSUMIT®, work here. Learn about the benefits of OPSUMIT®.
Phosphodiesterase type 5 inhibitors (PDE5 inhibitors) and soluble guanylate cyclase stimulators (sGCs) work here.
Prostacyclin, prostacyclin analogs, and prostacyclin receptor agonists work here.
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About Cheryl: Cheryl was diagnosed with PAH in 2011. She is a mother, grandmother, and photographer who loves exploring the outdoors. Cheryl is focused on looking forward, setting goals with her doctor, and knowing when to "sit out" and rest.
About Karla: Karla was diagnosed with PAH in 2003. She finds the greatest joy in spending time with family and loves anything that involves the theater. Karla knows the importance of setting goals with her "new normal" in mind.